Martinsburg, WV, is the county seat of Berkeley County, West Virginia, in the tip of the state’s Eastern Panhandle region. It is part of the Hagerstown-Martinsburg, MD-WV Metropolitan Statistical Area. Downtown Martinsburg offers unique local businesses, entertainment, dining, and shopping opportunities. Amtrak provides service to Martinsburg. It is also served by Interstate 81, U.S. Route 11, and W.V. Route 9. These routes lead directly to Harpers Ferry and Charles Town, WV, as well as Winchester, VA, and Hagerstown, MD.